GeneID: 491


Common Name: TOX4 Type: Gene
Chromosome: 14 (NC_000014.9) Locus: N/A
HUGO Symbol: TOX4 Full Name: TOX high mobility group box family member 4
Exons: 9 Introns: 8

TOX4 encodes a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. TOX4 is a component of the PTW/PP1 phosphatase complex and plays a role in the regulation of cell cycle and fate. It is implicated in the control of chromatin structure. Sequence variation in this gene associated with stroke outcomes in patients with sickle cell disease.

Synonyms: LCP1 , MIG7 , C14orf92 , KIAA0737


Sequence Viewer

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Publications / Origin

  1. Brewin JN, Rooks H, Gardner K, Senior H, Morje M, Patel H, Calvet D, Bartolucci P, Thein SL, Menzel S, Rees DC, Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC)., Haematologica, 106(6), 1770-1773, 2021 PubMed
Created on 2022-03-29 13:26:32, Last reviewed on (Show full history)

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