GeneID: 491



Names

Common Name: TOX4 Type: Gene
Chromosome: 14 (NC_000014.9) Locus: N/A
HUGO Symbol: TOX4 Full Name: TOX high mobility group box family member 4
Exons: 9 Introns: 8

Description:
TOX4 encodes a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. TOX4 is a component of the PTW/PP1 phosphatase complex and plays a role in the regulation of cell cycle and fate. It is implicated in the control of chromatin structure. Sequence variation in this gene associated with stroke outcomes in patients with sickle cell disease.

Synonyms: LCP1 , MIG7 , C14orf92 , KIAA0737

Comments:
N/A

Sequence Viewer

Note: The NCBI Sequence Viewer is not installed on the ITHANET servers but it is embedded in this page from the NCBI. Therefore, IthaGenes has no responsibility over any temporary unavailability of the service. In such a case, please Refresh the page or retry at a later stage.

Publications / Origin

  1. Brewin JN, Rooks H, Gardner K, Senior H, Morje M, Patel H, Calvet D, Bartolucci P, Thein SL, Menzel S, Rees DC, Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC)., Haematologica, 106(6), 1770-1773, 2021 PubMed
Created on 2022-03-29 13:26:32, Last reviewed on (Show full history)


Disclaimer: The information on this website is provided as an information resource only and must not to be used as a substitute for professional diagnosis and treatment. The ITHANET Portal and IthaGenes are not responsible or liable for any advice, course of treatment, diagnosis or any other information, services or products that an individual obtains through this website.