GeneID: 403
Names
Common Name: | SLC14A1 | Type: | Gene |
---|---|---|---|
Chromosome: | 18 (NC_000018.10) | Locus: | NG_011775.4 (SLC14A1) |
HUGO Symbol: | SLC14A1 | Full Name: | solute carrier family 14 member 1 (Kidd blood group) |
Exons: | 10 | Introns: | 9 |
Description:
The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system. Genetic variance in SLC14A1 associated with improved hydroxyurea (HU) response in patients with sickle cell disease based on observed alterations in inflammatory and renal dysfunction biomarkers.
Synonyms: JK , UT1 , UTE , HUT11 , Jk(b) , RACH1 , RACH2 , UT-B1 , HsT1341
Comments:
N/A
Sequence Viewer
Note: The NCBI Sequence Viewer is not installed on the ITHANET servers but it is embedded in this page from the NCBI.
Therefore, IthaGenes has no responsibility over any temporary unavailability of the service.
In such a case, please Refresh the page or retry at a later stage.
Publications / Origin
- Yahouédéhou SCMA, Neres JSDS, da Guarda CC, Carvalho SP, Santiago RP, Figueiredo CVB, Fiuza LM, Ndidi US, de Oliveira RM, Fonseca CA, Nascimento VML, Rocha LC, Adanho CSA, da Rocha TSC, Adorno EV, Goncalves MS, Sickle Cell Anemia: Variants in the , , and Genes Are Associated With Improved Hydroxyurea Response., Front Pharmacol, 11(0), 553064, 2020 PubMed
Created on 2020-10-13 12:21:22,
Last reviewed on (Show full history)
A/A | Date | Curator(s) | Comments |
---|---|---|---|
1 | 2020-10-13 12:21:22 | The IthaGenes Curation Team | Created |
Disclaimer: The information on this website is provided as an information resource only
and must not to be used as a substitute for professional diagnosis and treatment.
The ITHANET Portal and IthaGenes are not responsible or liable for any advice, course of treatment,
diagnosis or any other information, services or products that an individual obtains through this website.
IthaGenes was last updated on 2022-06-24 13:54:27