GeneID: 403

Names

Common Name:	SLC14A1	Type:	Gene
Chromosome:	18 (NC_000018.10)	Locus:	NG_011775.4 (SLC14A1)
HUGO Symbol:	SLC14A1	Full Name:	solute carrier family 14 member 1 (Kidd blood group)
Exons:	10	Introns:	9

Description:
The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system. Genetic variance in SLC14A1 associated with improved hydroxyurea (HU) response in patients with sickle cell disease based on observed alterations in inflammatory and renal dysfunction biomarkers.

Synonyms: JK , UT1 , UTE , HUT11 , Jk(b) , RACH1 , RACH2 , UT-B1 , HsT1341

Comments:
N/A

Number of entries/variants: 1

External Links

NCBI Gene	UniProtKB
PDB	HGNC
OMIM

IthaScore

Sequence Viewer

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Publications / Origin

Yahouédéhou SCMA, Neres JSDS, da Guarda CC, Carvalho SP, Santiago RP, Figueiredo CVB, Fiuza LM, Ndidi US, de Oliveira RM, Fonseca CA, Nascimento VML, Rocha LC, Adanho CSA, da Rocha TSC, Adorno EV, Goncalves MS, Sickle Cell Anemia: Variants in the , , and Genes Are Associated With Improved Hydroxyurea Response., Front Pharmacol, 11(0), 553064, 2020 PubMed

Created on 2020-10-13 12:21:22, Last reviewed on (Show full history)

A/A	Date	Curator(s)	Comments
1	2020-10-13 12:21:22	The IthaGenes Curation Team	Created

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