GeneID: 336


Common Name: RPS23P2-PCDH18 Type: Gene
Chromosome: 4 (NC_000004.12) Locus: N/A
HUGO Symbol: RPS23P2-PCDH18 Full Name: N/A
Exons: N/A Introns: N/A

Ribosomal Protein S23 (RPS23) belongs to the S12P family of ribosomal proteins, is a component of the 40S ribosomal subunit and functions in protein synthesis. RPS23 exists as multiple processed pseudogenes, one of which is RPS23 pseudogene 2 (RPS23P2). Processed pseudogenes are likely formed by reverse transcription and integration of processed mRNA into the genome by L1 transposons. Protocadherin 18 (PCDH18) belongs to the protocadherin gene family. These proteins contain up to seven cadherin-like motifs that are distinct from those present in classical cadherins, a single transmembrane domain, and distinct cytoplasmic domains. They are highly expressed in the nervous system. Genetic variance in the RPS23P2-PCDH18 intergenic region associated with haematological parameters (e.g., white blood cell count).

Synonyms: N/A


External Links

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Publications / Origin

  1. Fan W, Christensen M, Eichler E, Zhang X, Lennon G, Cloning, sequencing, gene organization, and localization of the human ribosomal protein RPL23A gene., Genomics, 46(2), 234-9, 1997 PubMed
  2. Balasubramanian S, Zheng D, Liu YJ, Fang G, Frankish A, Carriero N, Robilotto R, Cayting P, Gerstein M, Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes., Genome Biol., 10(1), R2, 2009 PubMed
  3. Chen WV, Maniatis T, Clustered protocadherins., Development, 140(16), 3297-302, 2013 PubMed
  4. Kim YK, Oh JH, Kim YJ, Hwang MY, Moon S, Low SK, Takahashi A, Matsuda K, Kubo M, Lee J, Kim BJ, Influence of Genetic Variants in EGF and Other Genes on Hematological Traits in Korean Populations by a Genome-Wide Approach., Biomed Res Int , 2015(0), 914965, 2015 PubMed
Created on 2019-12-10 09:56:59, Last reviewed on (Show full history)

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