Thalassaemia Modular Stratification System for personalized therapy of beta-thalassaemia (THALAMOSS)

Description

THALAMOSS (THALAssaemia MOdular Stratification System for personalized therapy of beta-thalassemia) is aimed at development of universal sets of markers and techniques for stratification of β-thalassaemia patients into treatment subgroups for (a) onset and frequency of blood transfusions, (b) choice of iron chelation, (c) induction of fetal hemoglobin, (d) prospective efficacy of gene-therapy. At present, no framework exists to guide therapeutic decisions and personalised treatment of β-thalassaemia

Organisation's Type

Research Project/Multi-Center Study