GeneID: 477


Common Name: miR-126 Type: Gene
Chromosome: 9 (NC_000009.12) Locus: NR_029695.1 (MIR126)
HUGO Symbol: MIR126 Full Name: microRNA 126
Exons: N/A Introns: N/A

MicroRNAs (miRNAs), such as MIR126, are small, non-coding RNAs that play key roles in the post-transcriptional regulation of gene expression by targeting specific mRNAs. miR-126 plays a role in regulating vascular integrity and has been associated with protective mechanisms against vascular damage. miR-126 expression was reduced in sickle cell disease (SCD) patients with leg ulcers, and was associated with an attenuating clinical profile, suggesting a protective role for sickle leg ulcer occurrence.

Synonyms: MIRN126 , mir-126 , miRNA126


External Links

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Publications / Origin

  1. Santos EDC, Melo GIV, Santana PVB, Quadros IGS, Yahouédéhou SCMA, Guarda CCD, Santiago RP, Fiuza LM, Carvalho SP, Adorno EV, Kaneto CM, Fonseca TCC, Goncalves MS, Aleluia MM, A Description of the Hemolytic Component in Sickle Leg Ulcer: The Role of Circulating miR-199a-5p, miR-144, and miR-126., Biomolecules, 12(2), 0, 2022 PubMed
Created on 2022-03-11 20:32:31, Last reviewed on (Show full history)

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