GeneID: 464
Names
Common Name: | CCDC26 | Type: | Gene |
---|---|---|---|
Chromosome: | 8 (NC_000008.11) | Locus: | NR_130917.1 (CCDC26) |
HUGO Symbol: | CCDC26 | Full Name: | CCDC26 long non-coding RNA |
Exons: | 4 | Introns: | N/A |
Description:
The CCDC26 gene contains 4 exons and spans over 328 kb. It is a non-coding RNA primarily known for its involvement in acute myeloid leukemia and other cancers. It may play a role in erythroid differentiation through the transcriptional regulation of globin genes. Suppression of CCDC26 RNA in K562 cells resulted in switching transcription of globin from the fetal type to the embryonic type by downregulation of FOG-2.
Synonyms: RAM
Comments:
N/A
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Publications / Origin
- Hirano T, Tsuruda T, Tanaka Y, Harada H, Yamazaki T, Ishida A, Long noncoding RNA CCDC26 as a modulator of transcriptional switching between fetal and embryonic globins., Biochim Biophys Acta Mol Cell Res, 1868(3), 118931, 2021 PubMed
Created on 2021-12-14 17:17:02,
Last reviewed on (Show full history)
A/A | Date | Curator(s) | Comments |
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1 | 2021-12-14 17:17:02 | The IthaGenes Curation Team | Created |
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IthaGenes was last updated on 2022-08-12 10:07:42