GeneID: 491
Names
| Common Name: | TOX4 | Type: | Gene |
|---|---|---|---|
| Chromosome: | 14 (NC_000014.9) | Locus: | N/A |
| HUGO Symbol: | TOX4 | Full Name: | TOX high mobility group box family member 4 |
| Exons: | 9 | Introns: | 8 |
Description:
TOX4 encodes a member of a family of transcriptional factors that contain the highly conserved high mobility group box (HMG-box) region. TOX4 is a component of the PTW/PP1 phosphatase complex and plays a role in the regulation of cell cycle and fate. It is implicated in the control of chromatin structure. Sequence variation in this gene associated with stroke outcomes in patients with sickle cell disease.
Synonyms: LCP1 , MIG7 , C14orf92 , KIAA0737
Comments:
N/A
Number of entries/variants: 1
Publications / Origin
- Brewin JN, Rooks H, Gardner K, Senior H, Morje M, Patel H, Calvet D, Bartolucci P, Thein SL, Menzel S, Rees DC, Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC)., Haematologica, 106(6), 1770-1773, 2021