GeneID: 489



Names

Common Name: CHSY3 Type: Gene
Chromosome: 5 (NC_000005.10) Locus: NM_175856.5 (CHSY3)
HUGO Symbol: CHSY3 Full Name: chondroitin sulfate synthase 3
Exons: 3 Introns: 2

Description:
CHSY3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities. Glycosylation is essential to brain development and function, while the dysfunction of glycosyltransferases has been implicated in neurodegenerative diseases. Sequence variation downstream the CHSY3 gene associated with stroke outcomes in patients with sickle cell disease.

Synonyms: CSS3 , CHSY2

Comments:
N/A

Sequence Viewer

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Publications / Origin

  1. Brewin JN, Rooks H, Gardner K, Senior H, Morje M, Patel H, Calvet D, Bartolucci P, Thein SL, Menzel S, Rees DC, Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC)., Haematologica, 106(6), 1770-1773, 2021 PubMed
Created on 2022-03-29 10:42:57, Last reviewed on (Show full history)


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