GeneID: 488



Names

Common Name: PHACTR2 Type: Gene
Chromosome: 6 (NC_000006.12) Locus: NM_001100164.2 (PHACTR2)
HUGO Symbol: PHACTR2 Full Name: phosphatase and actin regulator 2
Exons: 13 Introns: 12

Description:
PHACTR2 is a member of a family of four protein phosphatase 1 (PP1) and actin regulatory proteins, which are involved in a wide variety of physiological processes, including gene expression, muscle contraction, and glycogen metabolism. In the nervous system, this family of enzymes may regulate synaptic plasticity by controlling activity of a broad range of ion channels and signal transduction enzymes. Sequence variation in this gene associated with stroke outcomes in patients with sickle cell disease.

Synonyms: C6orf56

Comments:
N/A

Sequence Viewer

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Publications / Origin

  1. Allen PB, Greenfield AT, Svenningsson P, Haspeslagh DC, Greengard P, Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins., Proc Natl Acad Sci U S A, 101(18), 7187-92, 2004 PubMed
  2. Brewin JN, Rooks H, Gardner K, Senior H, Morje M, Patel H, Calvet D, Bartolucci P, Thein SL, Menzel S, Rees DC, Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC)., Haematologica, 106(6), 1770-1773, 2021 PubMed
Created on 2022-03-28 13:03:00, Last reviewed on (Show full history)


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