GeneID: 477
Names
| Common Name: | miR-126 | Type: | Gene |
|---|---|---|---|
| Chromosome: | 9 (NC_000009.12) | Locus: | NR_029695.1 (MIR126) |
| HUGO Symbol: | MIR126 | Full Name: | microRNA 126 |
| Exons: | N/A | Introns: | N/A |
Description:
MicroRNAs (miRNAs), such as MIR126, are small, non-coding RNAs that play key roles in the post-transcriptional regulation of gene expression by targeting specific mRNAs. miR-126 plays a role in regulating vascular integrity and has been associated with protective mechanisms against vascular damage. miR-126 expression was reduced in sickle cell disease (SCD) patients with leg ulcers, and was associated with an attenuating clinical profile, suggesting a protective role for sickle leg ulcer occurrence.
Synonyms: MIRN126 , mir-126 , miRNA126
Comments:
N/A
Number of entries/variants: 0
Publications / Origin
- Santos EDC, Melo GIV, Santana PVB, Quadros IGS, Yahouédéhou SCMA, Guarda CCD, Santiago RP, Fiuza LM, Carvalho SP, Adorno EV, Kaneto CM, Fonseca TCC, Goncalves MS, Aleluia MM, A Description of the Hemolytic Component in Sickle Leg Ulcer: The Role of Circulating miR-199a-5p, miR-144, and miR-126., Biomolecules, 12(2), 0, 2022