GeneID: 44


Common Name: SMAD3 Type: Gene
Chromosome: 15 (NC_000015.10) Locus: NG_011990.1 (SMAD3)
HUGO Symbol: SMAD3 Full Name: SMAD family member 3
Exons: 9 Introns: 8

SMAD3 is a member of the SMAD family of proteins, which act as transcriptional regulators in the transforming growth factor β (TGFβ) signalling pathway. TGFβ/SMAD3 signalling may play a role in the regulation of carcinogenesis. Polymorphisms in the SMAD3 gene associated with HbF levels in African American sickle cell patients.

Synonyms: HsT17436 , JV15-2


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Publications / Origin

  1. Massagué J, Seoane J, Wotton D, Smad transcription factors., Genes Dev. , 19(23), 2783-810, 2005 PubMed
Created on , Last reviewed on 2016-04-25 14:57:04 (Show full history)

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