GeneID: 413
Names
| Common Name: | SVIL | Type: | Gene |
|---|---|---|---|
| Chromosome: | 10 (NC_000010.11) | Locus: | NG_033998.1 (SVIL) |
| HUGO Symbol: | SVIL | Full Name: | supervillin |
| Exons: | 36 | Introns: | 35 |
Description:
The SVIL gene encodes supervillin, which belongs to the villin/gelsolin superfamily of actin-binding proteins involved in many cellular processes. Supervillin is tightly associated with both actin filaments and plasma membranes, suggesting that it forms a link between the actin cytoskeleton and the membrane. Genetic variance in RAD51B associated with F-cell levels in sickle cell anaemia.
Synonyms: N/A
Comments:
N/A
Number of entries/variants: 1
Publications / Origin
- Bhatnagar P, Purvis S, Barron-Casella E, DeBaun MR, Casella JF, Arking DE, Keefer JR, Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients., J. Hum. Genet. , 56(4), 316-23, 2011