GeneID: 308



Names

Common Name: PDGFRA-KIT Type: Intergenic Region
Chromosome: 4 (NC_000004.12) Locus: N/A
HUGO Symbol: PDGFRA-KIT Full Name: N/A
Exons: N/A Introns: N/A

Description:
PDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. KIT (KIT proto-oncogene, receptor tyrosine kinase) encodes the human homolog of the proto-oncogene c-kit, a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Genetic variance in the PDGFRA-KIT intergenic region associated with haematological parameters (e.g., haematocrit level and red blood cell count).

Synonyms: N/A

Comments:
N/A

External Links

Sequence Viewer

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Publications / Origin

  1. Kim YK, Oh JH, Kim YJ, Hwang MY, Moon S, Low SK, Takahashi A, Matsuda K, Kubo M, Lee J, Kim BJ, Influence of Genetic Variants in EGF and Other Genes on Hematological Traits in Korean Populations by a Genome-Wide Approach., Biomed Res Int , 2015(0), 914965, 2015 PubMed
Created on 2019-11-18 15:03:04, Last reviewed on (Show full history)


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