GeneID: 125
Names
Common Name: | OR51B6 | Type: | Gene |
---|---|---|---|
Chromosome: | 11 (NC_000011.10) | Locus: | N/A |
HUGO Symbol: | OR51B6 | Full Name: | olfactory receptor family 51 subfamily B member 6 |
Exons: | 1 | Introns: | N/A |
Description:
Olfactory receptors (ORs) are members of a large family of G-protein-coupled receptors (GPCR) that transverse the membrane seven times and are located on the sensory neurons of nasal epithelium. The OR gene family is the largest in the genome and exists as clusters of genes in specific genomic locations. ORs bind to odorant molecules and transduce signals via a G protein, in turn activating downstream effector molecules that trigger the perception of smell. The olfactory system is highly discriminating and each OR can be activated by multiple odorants of similar structure. The ORs are grouped into subfamilies based on the type of odorant structure detected. OR51B6 encodes the olfactory receptor family 51 subfamily B member 6. The nomenclature assigned to the OR genes and proteins for this organism is independent of other organisms.
Synonyms: N/A
Comments:
N/A
Number of entries/variants: 9
IthaScore
Publications / Origin
- Malnic B, Godfrey PA, Buck LB, The human olfactory receptor gene family., Proc. Natl. Acad. Sci. U.S.A. , 101(8), 2584-9, 2004
- Niimura Y, Nei M, Evolutionary dynamics of olfactory and other chemosensory receptor genes in vertebrates., J. Hum. Genet. , 51(6), 505-17, 2006
- Solovieff N, Milton JN, Hartley SW, Sherva R, Sebastiani P, Dworkis DA, Klings ES, Farrer LA, Garrett ME, Ashley-Koch A, Telen MJ, Fucharoen S, Ha SY, Li CK, Chui DH, Baldwin CT, Steinberg MH, Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster., Blood , 115(9), 1815-22, 2010
A/A | Date | Curator(s) | Comments |
---|---|---|---|
1 | 2016-04-27 15:50:00 | The IthaGenes Curation Team | Created |